Estimated cardiovascular risk correlates with lipid profil in Brazilian patients with type 2 diabetes
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The aim of this cross-sectional multicentre study conducted on 1382 patients from 13 public outpatient endocrinology clinics in Brazil was to stratify the estimated cardiovascular risk (eCVR) in a population of type 2 diabetes according to the Framingham prediction equation. The overall 10-year eCVR in patients with type 2 diabetes was 21.4%, men exhibiting a higher eCVR than women. The median number of risk factors present was three, without gender differences. The commonest risk factor was elevated low-density lipoprotein cholesterol (LDL-C). A higher eCVR was found in overweight and obese subjects. eCVR was unrelated to age or a specific type of diabetes treatment and correlated with diabetes duration, body mass index, serum creatinine, and triglycerides levels, but not with HbA1c nor with fasting or postprandial glucose. Lastly, eCVR was significantly higher in patients with retinopathy, while tending to be higher in those presenting with microalbuminuria. In conclusion, in this Brazilian population with type 2 diabetes, eCVR was correlated with the lipid profile but not with glycaemic control parameters, while being higher in patients with microvascular chronic complications.
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