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Moderate and severe hypertriglyceridaemia associated with obesity, diabetes mellitus and vascular disease in the Spanish working population

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2009-july-28

This cross-sectional study of 594,701 Spanish workers (72% males) from all geographical areas was conducted to evaluate the prevalence, risk factors, and vascular disease associated with moderate and severe hypertriglyceridaemia in an active working population. Among the study population, 16% had mild hypertriglyceridaemia (HTg), 1.1% had moderate HTg, and 0.03% had severe HTg, with 90% of workers with hypertriglyceridaemia being males. The following factors were associated with HTg: age, obesity, type 1 and type 2 diabetes, alcohol consumption, and vascular disease. For each HTg category, cardiovascular risk factors gradually increased. While obesity was the major independent predictor of mild HTg, diabetes was a predictor of moderate HTg and severe HTg. Multivariate analyses revealed that, even after adjusting for other risk factors, HTg was gradually associated with vascular disease. Thus, preventive programmes targeting HTg and associated vascular disease should consider obesity-diabetes control as a prime objective.

Abstract

Keywords:
Cardiovascular risk – Diabetes – Obesity – Hypertriglyceridaemia

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