Nonfasting triglycerides associated with risk of ischaemic stroke
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This prospective study was designed to test the hypothesis that increased levels of nonfasting triglycerides, a marker of remnant lipoproteins, are associated with ischaemic stroke in the general population. To this end, data from subjects participating in the Copenhagen City Heart Study, initiated in 1976 and followed-up through July 2007, were evaluated. Among the 13,956 participants, 1529 developed ischaemic stroke. Cumulative incidence of ischaemic stroke significantly increased with increasing levels of nonfasting triglycerides in both men and women. Absolute 10-year risk of ischaemic stroke ranged from 2.6% in men aged <55 years with nonfasting triglyceride levels <89 mg/dL to 16.7% in men aged ≥55 years with levels ≥443 mg/dL and from 1.9% in women aged <55 years with nonfasting triglyceride levels <89 mg/dL to 12.2% in women aged ≥55 years with levels ≥443 mg/dL. In conclusion, nonfasting triglyceride levels are associated with incident ischaemic stroke.
Abstract
