Deleterious alterations in lipid metabolism associated with increased risk of ischaemic stroke in women
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2007-mar-30
In a prospective cohort study among 27937 apparently healthy US women aged ≥45 years, plasma lipid measurements at baseline were categorized into quintiles. During the 11-year follow-up, stroke occurrence (self-reported and confirmed by medical record review) was prospectively assessed. Cox proportional hazard models revealed that total cholesterol, low-density lipoprotein cholesterol, total cholesterol to high-density lipoprotein cholesterol ratio, and non-high-density lipoprotein cholesterol (total-C minus HDL-C) were all strong predictors of increased risk of ischaemic stroke.
Abstract
