Pathophysiological aspects

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Changes in body shape, fat distribution with increasing parity

 

Mutations of the ghrelin gene in people with the metabolic syndrome

 

Ghrelin levels influenced by lifestyle factors

 

Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5

 

Insulin secretion in hyperlipoproteinemias

 

Novel mechanism of heart disease: myocardial steatosis - (04/05/06)

 

Increased plasma leptin levels associated with insulin resistance (IR), inflammatory and haemostatic risk factors for cardiovascular disease (CVD) - (28/06/06)

 

The cat as a model for studying human obesity and diabetes - (10/10/06)

 

Characterization of lipid phenotypes in children for the prevention of coronary heart disease - (17/10/06)

 

High prevalence of postchallenge hyperglycaemia in non-alcoholic fatty liver disease patients - (30/10/06)

 

Specific pharmacologic interventions are required for reducing metabolic syndrome risk - (31/10/06)

 

Plasma adiponectin levels inversely related to coronary artery disease severity but not to hypertension in nondiabetic patients - (06/11/06)

 

Simple fasting state measures to assess the progression from normal glucose tolerance to impaired glucose tolerance and to type 2 diabetes - (08/11/06)

 

Metabolic syndrome as independent risk factor for erectile dysfunction in a large cohort study - (31/01/07)

 

Metabolic syndrome shown to enhance sympathetic activation in congestive heart failure - (01/02/07)

 

Fat cell enlargement as an independent marker of insulin resistance in non-diabetic subjects - (03/02/07)

 

C-reactive protein as an "intermediate phenotype" for inflammation - (04/02/07)

 

Dietary energy density as an independent predictor of obesity, elevated fasting insulin, and metabolic syndrome in US adults - (20/02/07)

 

Chronic work stress linked to general and central obesity - (21/02/07)

 

Acquired obesity associated with changes in lipid metabolism independent of genetic effects - (27/03/07)

 

Impaired substrate switching and reduced muscle mitochondrial content in subjects with a family history of type 2 diabetes - (05/04/07)

 

Progressive metabolic derangement of glucose tolerance first detected during pregnancy mimics the pathogenesis of type 2 diabetes - (06/04/07)

 

Target organ changes in essential hypertensive patients amplified by the metabolic syndrome across age groups - (10/04/07)

 

Metabolic syndrome associated with increased risk of venous thromboembolism - (13/04/07)

 

Reduced plasma natriuretic peptide levels as a manifestation of the metabolic syndrome - (17/04/07)

 

Changes in weight associated with parallel changes in albuminuria in a population-based longitudinal study - (25/04/07)

 

Impaired fasting glucose as a metabolic marker of impaired cognitive function in the elderly - (27/04/07)

 

Glomerular hyperfiltration associated with high metabolic risk - (04/05/07)

 

Untreated masked hypertensive subjects detected by home blood pressure measurement at increased risk for subclinical arterial damage - (10/05/07)

 

Circulating levels of endothelial adhesion molecules linked to the risk of developing type 2 diabetes - (14/05/07)

 

Metabolic endotoxaemia triggers body weight gain and diabetes in mice - (16/05/07)

 

Magnitude of risk factors for type 2 diabetes and cardiovascular disease varies markedly in moderately obese subjects - (24/05/07)

 

Midlife measures of central obesity and of hypertension linked to cognitive decline with age - (28/05/2007)

 

Plasma cytokines as independent predictors of atherosclerosis in humans - (01/06/2007)

 

Obstructive sleep apnoea associated with insulin resistance, inflammation and metabolic syndrome independently of body mass index - (12/06/2007)

 

Insulin resistance linked to the components of the metabolic syndrome in Black and White youth, and to biomarkers of endothelial function in White youth - (15/06/2007)

 

Circulating adiponectin levels shown to be a useful predictor of coronary endothelial function - (19/06/2007)

 

Microvascular vasodilator function is impaired in obese patients, with little further impairment in impaired fasting glucose and type 2 diabetes patients - (22/06/2007)