Relation Between the Metabolic Syndrome and Ischemic Stroke or Transient Ischemic Attack. A Prospective Cohort Study in Patients With Atherosclerotic Cardiovascular Disease.
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In this study from Israel, 14 284 patients with coronary heart disease, of which 3703 (26%) had the metabolic syndrome without diabetes and 3500 others (25%) had diabetes, underwent a follow-up for stroke or.transient ischaemic attack (TIA) over 4.8 to 8.1 years. Adjusting for stroke risk factors, patients with the metabolic syndrome exhibited a 1.49-fold increased risk of cerebrovascular events, whereas those with frank diabetes had a 2.29-fold increased risk. Among the metabolic syndrome components, impaired fasting glucose and hypertension were the strongest predictors of cerebrovascular events. The risk for stroke or TIA associated with the metabolic syndrome was more pronounced in women.
Authors : Koren-Morag N, Goldbourt U, Tanne D.
PMID/ref : Stroke. 2005 Jun 2; Epub ahead of print.
